"Despite that we did not test each SLC in each platform, and we did not cover all available platforms, we can conclude that nanobodies were the best approach to generate SLC binders. Using this approach, we obtained the most robust binders fulfilling all our validation criteria."
ReSOLUTE Consortium
Research Empowerment on Solute Carriers
*all of the nanobodies in this study were provided by the NSF-UZH.
"Generation of nanobodies by immunization of alpaca at the Nanobody Service Facility of the UZH has been very valuable for leadXpro. We use the nanobodies directly or converted into Pro-Macrobodies as a tool to progress our membrane protein X-ray and cryo-EM structure projects. A big thank to the very competent work of the team of Saša Štefanić!"
Michael Hennig, CEO leadXpro
"I had the pleasure to work with Dr Stefanic and the NSF with the ultimate goal of generating nanobodies targeting the cyst wall of Giardia lamblia, a parasite of global medical importance, as part of a UZH-funded project. The NSF provided all the support and advice needed for the successful completion of this project. Further input for follow-up experiments including nanobody production, validation and possible applications was also generously shared, beyond the call of duty. I am extremely satisfied with the service provided by the NSF and have warmly recommended it to colleagues at both UZH and UniBern where I currently lead my own group."
Prof. Dr. Carmen Faso
"Our research on bacterial pathogens greatly profits from NFS platform to conduct alpaca immunization at the University of Zurich. We highly appreciate the flexibility, reliablity and overall quality of the services provided by Saša Štefanić and his team."
Prof. Dr. Markus Seeger
